Paccal Vet, which is being developed to treat cancer in dogs, is a combination of Oasmia's patented excipient XR-17 and chemotherapeutic substance
paclitaxel. XR-17 is developed to improve the solubility of substances, such as
paclitaxel, without having the side effects associated with lipid soluble formulations, in which
paclitaxel is usually dissolved.
Our aim was to present a rare case of immune thrombocytopenic purpura (ITP) following
paclitaxel treatment.
The team scanned 829 genes in breast cancer cells and identified six genes which, if missing or faulty, could prevent the cancer cells from responding to
paclitaxel.
Nine months after the procedure, patients who had received the Sequent Please
paclitaxel balloon and BMS had narrower channels inside the stent and higher rates of in-stent restenosis, revascularization and heart attack than those who received the DES.
Elesclomol is currently being studied in combination with
paclitaxel in a Phase III trial in metastatic melanoma, which completed enrollment earlier this year.
A simple, rapid and sensitive high-performance liquid chromatographic method is described for determination of
Paclitaxel (PCL) from coated stent surface using a reverse phase X-terra [C.sub.18] (5 [micro]m) column at 227 nm and using acetonitrile, methanol and water in the ratio of 60:5:35 (v/v) as a mobile phase following single-step extraction from Phosphate buffer saline (PBS) pH 7.4 with dichloromethane.
Randomized phase III trial in advanced endometrial carcinoma of surgery and volume-directed radiation followed by cisplatin and doxorubicin with or without
paclitaxel: a Gynecologic Oncology Group study.
A weekly dose of
paclitaxel prolongs overall survival of breast cancer patients more effectively than weekly docetaxel or the standard 3-week schedule for either taxane, according to investigators of a randomized trial comparing these adjuvant regimens in nearly 5,000 women.
In a study of women with axillary lymph node-positive or high-risk, lymph node-negative breast cancer, treatment with
paclitaxel every week rather than every 3 weeks following adjuvant chemotherapy improved both overall and disease-free survival.
At the time of Janet's diagnosis and treatment, we were investigating the potential benefit of fighting cancer with a compound called
paclitaxel found in the bark of Pacific yew trees and bushes.
Medicines and Healthcare products Regulatory Agency (MHRA) for its Clinical Trial Application (CTA) to begin a clinical trial using intravenous administration of REOLYSIN(R) in combination with
paclitaxel and carboplatin in patients with advanced cancers including melanoma, lung, and ovarian.