Physiological and Histopathological studies on Bisphenol-A compound as
xenoestrogen in male albino rats.
The use of biomarkers of cumulative EDC exposure, such as the total effective
xenoestrogen burden (TEXB; Fernandez et al.
Seoul National University's Graduate School of Public Health released a study Thursday that showed touching thermal-paper rolls with bare hands a widely used as store sales receipts or for queue slips at banks and other places a doubles the risk of absorbing bisphenol A (BPA), a type of
xenoestrogen in the paper.
The
xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive tract.
Low levels of BPA, however, act additively with
xenoestrogen and natural estrogens (Silva, Rajapakse, & Kortenkamp, 2002; Soto, Chung, & Sonnenschein, 1994; Soto, Fernandez, Luizzi, Oles Karasko, & Sonnenschein, 1997; Tollefesen, 2002).
"It's thought these act as a '
xenoestrogen' - a substance that acts like the oestrogen hormone - increasing breastcancer risk.
Conner |Middelmann-Whitney "It's thought these act as a '
xenoestrogen' - a substance that acts like the oestrogen hormone - increasing breastcancer risk.
Increased oviposition with increasing sources of
xenoestrogen source is a logical trend given the estrogenic effects of these compounds in living organisms.
One example is bisphenol-A, a major component in plastic containers, which was shown to be a
xenoestrogen, a breast cancer-causing agent.
Cancers specific to female reproductive organs such as the breast, uterus and ovary, are associated with higher long-term exposure to oestrogen, and numerous studies have shown that environmental
xenoestrogen presence and exposure is higher in urban areas.