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This provides differentiation from additional entities that typically include giant cells: cherubism, central giant cell granuloma, giant cell tumor in the setting of paget's disease, and aneurysmal bone cyst.
These characteristics confirm the diagnosis of cherubism. Since the disorder spontaneously regresses after puberty, there was no need to perform surgery.
The role of SH3BP2 in the pathophysiology of cherubism. Orphanet J Rare Dis 2012;7(Suppl 1):S5.
(67-70) In these groups of disorders, some identifiable pathogenetic factors include viral infection or autoimmune diseases66 and fibrous dysplasia or familial cherubism. (69,71) However, some morphologically identical inflammatory pseudotumors are associated with no explanatory factors and must be classified as idiopathic.
Differential diagnosis includes giant cell reparative granuloma, cherubism, true giant cell tumor, aneurismal bone cyst, and solitary bone cyst (61.
Christ-Siemens-Touraine syndrome, Stikle syndrome, cherubism, and ectodermal dysphasia were identified.
But journalist Vikki Lucas, who has a rare genetic condition called cherubism, believes it's not her face she should change but society's attitude.
Plus,a woman with the rare genetic condition cherubism talks about why she refuses any treatment,and believes society should be less intolerant of those who simply look different.(BBCTWO,9pm)
Cherubism Cherubism is characterized by symmetric bilateral enlargement of the mandible.
`My parents had never heard of cherubism. Bizarrely, it was the first time it had been diagnosed in our family.
They commonly include lesions of primary or secondary hyperparathyroidism, fibrous dysplasia including cherubism, Central Giant Cell Granuloma, and aneurysmal bone cyst.
A rare variant of this entity called Cherubism is a familial form affecting children and adolescents and typically involving only the maxilla and mandible (2,15) .
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