An interesting and related study found that
crocin, a saffron apocarotenoid, was helpful in reducing diabetic cataracts.
Preventive effect of
crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats.
Effects of saffron extract and
crocin on anthropometrical, nutritional and lipid profile parameters of rats fed a high-fat diet.
Extraction optimization of bioactive compounds (
crocin, geniposide and total phenolic compounds) from Gardenia (Gardenia jasminoides Ellis) fruits with response surface methodology.
Six trials used saffron extracts standardised for safranal and/or
crocin, while the remaining studies did not report standardisations for the active constituents.
GSK said India remained an important market for it and the company will continue to invest in growth opportunities for its OTC and Oral Health brands there, which include
Crocin, Eno and Sensodyne.
Numerous studies have shown that treatment with antioxidant substances such as vitamins E and C, (5,9) N-acetyl-cysteine, (10) and
crocin and safranal (11) can decrease the oxidative stress and the mortality rate related to OPI-induced toxicity.
Neuroprotective effect of
crocin on acrylamide-induced cytotoxicity in PC12 cells.
The following reference standards were provided by the National Institutes for Food and Drug Control:
Crocin I (111588-200501) and
Crocin II (111589-200802).
Vanderheyden, "Modulation of calcium signaling of angiotensin [AT.sub.1], endothelin ETA, and ETB receptors by silibinin, quercetin,
crocin, diallyl sulfides, and ginsenoside Rb1," Planta Medica, vol.
Du, "A new method research for determination of natural pigment
crocin yellow in foods by solid-phase extraction ultrahigh pressure liquid chromatography," Journal of Chromatography A, vol.