Forkhead box protein M1 (FOXM1) is a typical cell proliferation-associated transcription factor, which stimulates cell proliferation by promoting S-phase and M-phase entries in cell cycle transition (23).
Immunoexpression of interleukin 17, transforming growth factor [beta]1, and
forkhead box P3 in periapical granulomas, radicular cysts, and residual radicular cysts.
Immunohistochemically, the tumors were positive for a-inhibin (5/6) [Figure 1]d, calretinin (5/6), CD99 (6/6), and
forkhead box L2 (FOXL2, 6/6) [Figure 1]e and negative for epithelial membrane antigen (0/6).
Analysis of the genes PAX6 (11p13), PITX2 (or RIEG1) (4p25-26), PITX3 (RIEG/PITX homeobox gene family) (10q25), CYP1B1 (cytochrome P4501B1 gene) (2p22), FKHL7 (
Forkhead transcription factor) and B3GALTL gene (13q12.3) revealed no deletions or duplications in these genes.
For an association study, four genes were selected based on high gene expression differences during RNA-seq analysis and their location within QTLs related to percentage of fibers I, IIA, and IIB (troponin T2 [TNNT2];
forkhead box O1 [FOXO1]).
IGF-1 has been shown to; (1) induce androgen synthesis and increase the cutaneous availability of dihydrotestosterone; (2) disinhibit the
forkhead box Ol (FoxOl) transcription factor, which normally suppresses the androgen receptor; and (3) activate peroxisome proliferator-activated receptor-gamma, liver X receptor-alpha, and sterol regulatory element binding protein-1c (SREBP-1c).
Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol.
Helicobacter pylori-associated regulation of
forkhead transcription factors FoxO1/3a in human gastric cells.
In the next downstream pathways, the activated AKT phosphorylates and inhibits the
forkhead transcription factor, FOXO3a.
The
forkhead box (Fox) belongs to a large and diverse group of transcription factor families.
Forkhead c2 (Foxc2) is a member of the winged spiral transcription factor family.