fluorouracil

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fluor·o·u·ra·cil

(flo͝or′ō-yo͝or′ə-sĭl, flôr′-)

An antineoplastic agent, C₄H₃FN₂O₂, used especially in the treatment of cancers of the skin, breast, and digestive system.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

fluorouracil

(ˌflʊərəʊˈjʊərəsɪl)

a chemotherapy drug used in the treatment of cancer, which operates by interfering with the abnormal growth of cells

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

fluor•o•u•ra•cil

(ˌflʊər əˈyʊər ə sɪl, ˌflɔr-, ˌfloʊr-)

n.

a pyrimidine analog, C₄H₃FN₂O₂, used in the treatment of certain cancers.

[1955–60]

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Noun

fluorouracil - an antimetabolite used to treat certain cancers

antimetabolite - an antineoplastic drug that inhibits the utilization of a metabolite

Translations

fluorouracil

n fluorouracilo

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antimetabolite

References in periodicals archive ?

These results "indicate that treating a patient with a single course of fluorouracil would reduce the subsequent number of spot treatments and benefit care of patients with multiple AKs for longer than 2 years," concluded Dr.

Topical fluorouracil shows long-term benefit for AKs

Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer.

Neoadjuvant chemotherapy: role in locoregionally advanced oral cancers

Fluorouracil (Adrucil) is approved for the treatment of colorectal and multiple other cancers.

Rectal ca: neoadjuvant capecitabine equals IV 5-FU

In most of the cases of breast cancer the prescribed chemotherapy regimen was six cycles of FAC (Fluorouracil + Adriamycin + Cyclophosphamide) administered every three weeks.

RATIONAL USE OF 5-FLUOROURACIL IN CHEMOTHERAPY AND BREAST Cancer

Although capecitabine is slightly more expensive than fluorouracil, it is cheaper to use because it can be taken by mouth outside of hospital.

United Kingdom : Two new cancer treatments approved for use in the NHS

A statistical analysis of cell regeneration showed a 15.4 percent reduction in new brain cells following fluorouracil, a 30.5 percent reduction following cyclophosphamide, a 22.4 percent reduction following doxorubicin, and a 36 percent reduction following paclitaxel.

Chemo drugs may lead to cognitive decline

But the couple were not told of the risk of cardio-toxicity with 5 - Fluorouracil.

CHEMO RISKS NOT DISCUSSED

Prospective randomized trial comparing mitomycin, cisplatin, and protracted venousinfusion fluorouracil (PVI 5-FU) with epirubicin, cisplatin, and PVI 5-FU in advanced esophagogastric cancer.

Chemotherapy in advanced gastric cancer

This compared with 81% who received the standard therapy with fluorouracil.

Drug cocktail could cut breast cancer deaths, claim researchers

* Antineoplastic agents (fluorouracil, methotrexate, procarbazine).

Medications, sun may not mix

The regulator has approved the product as monotherapy and in combination with chemotherapy regimen platinum and fluorouracil. The approval is for first-line treatment of metastatic or with unresectable, recurrent head and neck squamous cell carcinoma as monotherapy in patients whose tumours express the biomarker PD-L1.