fluoroquinolone


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fluor·o·quin·o·lone

 (flo͝or′ə-kwĭn′ə-lōn′, flôr′-)
n.
Any of a group of broad-spectrum antibiotics that are fluorinated quinolones, the first of which was nalidixic acid.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
Translations

fluoroquinolone

n fluoroquinolona
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
The group of fluoroquinolones with its most famous member ciprofloxacin is such a case: Fluoroquinolones are some of the most frequently used broad-spectrum antibacterial antibiotics, and usually prescribed for respiratory, urinary or ear infections.
Ciprofloxacin has dramatic effects on the mitochondrial genome
Among these, 2,350 (65%) were fluoroquinolone nonsusceptible, 418 (12%) were MDR, and none had resistance to ceftriaxone.
Emergence of Extensively Drug-Resistant Salmonella Typhi Infections Among Travelers to or from Pakistan--United States, 2016-2018
FLUOROQUINOLONES have caused at least 67 cases of life-threatening hypoglycemic coma, including 13 deaths and 9 permanent and disabling injuries, according to an internal safety review by the Food and Drug Administration.
Fluoroquinolones can cause fatal hypoglycemia, FDA warns
The low blood glucose levels induced by fluoroquinolone antibiotics can result in health problems, including coma, especially among older people and those with diabetes who are on medications to reduce blood glucose.
FDA Requires Safety Label Changes for Fluoroquinolones; Changes will describe hypoglycemic coma and clarify and identify mental health side effects
At our institution as well as other military and civilian medical centers, it is common to use the antipseudomonal beta lactam piperacillin-tazobactam in combination with a fluoroquinolone for empiric gram-negative coverage.
A retrospective analysis: Do bacterial culture and sensitivity data supportempiric use of piperacillin-tazobactam and antipseudomonal fluoroquinolones in hospitalized patients?
Interestingly, the number of fluoroquinolone prescriptions did not decrease after the box warning for tendonitis and tendon rupture in 2008, or following the special warning about peripheral neuropathy in 2013.
Antibiotic warning updated
After conducting a safety review of the drugs, the FDA concluded that fluoroquinolone should be reserved for those patients who do not have alternative treatment options, in light of the findings that the antibiotics--when used systemically in either tablet, capsule, or injectable form--are associated with "disabling and potentially permanent serious side effects" that can occur together.
FDA warns against routine fluoroquinolone use
To evaluate the feasibility of predicting resistance to fluoroquinolones in GBS directly from short-read genome data, we first searched the literature for articles reporting mutations in genes parC, parE, gyrA, and gyrB that have been associated with fluoroquinolone resistance and created a working database of known mutations conferring resistance to this antimicrobial class.
Fluoroquinolone resistance among clonal complex 1 group B Streptococcus strains
The results of DNA gyrase sensitivity testing of this mutant revealed that the development of fluoroquinolone resistance is not the result of mutation in DNA gyrase.
Overexpression of Salmonella enterica serovar Typhi recA gene confers fluoroquinolone resistance in Escherichia coli DH5[alpha]
Tolerability of Fluoroquinolone Antibiotics: Past, Present and Future.
Incidence of fluoroquinolones induced psychotic disorders in patients admitted to department of medicine in a general hospital setup
Third and fourth generation fluoroquinolone antibacterials: a systematic review of safety and toxicity profiles.
Fluoroquinolones in India--are we prescribing it right: a cost variation study. (Research Article)

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