lupus erythematosus

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Related to lupus erythematosus: discoid lupus erythematosus, Cutaneous lupus erythematosus

lupus er·y·the·ma·to·sus

(ĕr′ə-thē′mə-tō′səs, -thĕm′ə-)

2. Any of several other autoimmune disorders typically characterized by reddish, scaly lesions on the skin, especially:

a. A chronic cutaneous form characterized by patchy lesions that form especially on the head and neck, with accompanying scarring and pigmentation changes; discoid lupus erythematosus.

b. A form caused by exposure to a drug and resolving with discontinuance of the drug, characterized by signs and symptoms similar to those of systemic lupus erythematosus; drug-induced lupus erythematosus.

[New Latin lupus erythēmatōsus : lupus + erythēmatōsus, erythematous.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

lupus erythematosus

(ˌɛrɪˌθiːməˈtəʊsəs)

(Pathology) either of two inflammatory diseases of the connective tissue. Discoid lupus erythematosus is characterized by a scaly rash over the cheeks and bridge of the nose; disseminated or systemic lupus erythematosus affects the joints, lungs, kidneys, or skin. Abbreviation: LE

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

lu′pus er•y•the•ma•to′sus

(ˌɛr əˌθi məˈtoʊ səs, -ˌθɛm ə-)
n.

any of several autoimmune diseases, esp. systemic lupus erythematosus, characterized by red, scaly skin patches.

[1855–60; < New Latin]

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Noun

lupus erythematosus - a chronic inflammatory collagen disease affecting connective tissue (skin or joints)

autoimmune disease, autoimmune disorder - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues

lupus - any of several forms of ulcerative skin disease

Translations

lu·pus er·y·the·ma·to·sus

n. lupus eritematoso sistémico, condición caracterizada por episodios febriles que afecta las vísceras y el sistema nervioso;

n. lupus eritematoso discoide, condición caracterizada por placas escamosas de bordes enrojecidos que causa irritación de la piel.

English-Spanish Medical Dictionary © Farlex 2012

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References in periodicals archive ?

Tulip 2 was the second phase III trial designed to assess the safety and efficacy of anifrolumab as a treatment for adults with moderate-to-severe systemic lupus erythematosus.

AstraZeneca achieves primary endpoint in anifrolumab phase III Tulip two trial

Systemic lupus erythematosus and CD tend to be associated with many autoimmune diseases, including type 1 diabetes, autoimmune thyroid diseases, and connective tissue diseases (23, 24).

Serological screening for celiac disease in children with systemic lupus erythematosus

Release date- 29082019 - AstraZeneca today announced that the Phase III TULIP 2 trial for anifrolumab, a potential new medicine for the treatment of systemic lupus erythematosus (SLE), met its primary endpoint, achieving a statistically-significant and clinically-meaningful reduction in disease activity versus placebo, with both arms receiving standard of care.

AstraZeneca - Anifrolumab Phase III trial meets primary endpoint in systemic lupus erythematosus

Mene Pangalos, Executive Vice President, BioPharmaceuticals R&D, said: "Systemic lupus erythematosus is a debilitating autoimmune disease, but only one new treatment has been approved in the last 60 years.

Anifrolumab Phase III trial meets primary endpoint in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that disproportionately affects women and minorities.

Racial Disparities in Mortality Associated with Systemic Lupus Erythematosus--Fulton and DeKalb Counties, Georgia, 2002-2016

This US FDA approval extends the current indication in the US for the IV formulation of Benlysta to patients aged five years and older with active, autoantibody-positive, systemic lupus erythematosus (SLE) who are receiving standard therapy.

GSK wins US FDA priority review approval for the intravenous (IV) formulation of Benlysta in children with lupus

A total of 97 patients were selected from both outpatient and inpatient department after sample size calculation (95 % Confidence level, 05 % margin of error and taking frequency of pulmonary arterial hypertension in Systemic Lupus Erythematosus of 23%.

Frequency and predictors of pulmonary hypertension in patients with Systemic Lupus Erythematosus

Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune disease predominantly affecting women, and its clinical features always include hematological abnormalities, skin and joint diseases, renal disease, and neuropsychiatric complications.[1],[2] SLE is characterized by the development of dysregulated autoreactive B-cell-derived autoantibodies directed against nuclear and cellular components and the activation of complex inflammatory cascades, thereby resulting in multisystem organ damage.[1],[2]

Association of HLA-DR3 and HLA-DR15 Polymorphisms with Risk of Systemic Lupus Erythematosus

Hamid Pediatric systemic lupus erythematosus Retrospective analysis of clinico-laboratory parameters and their association with Systemic Lupus Erythematosus Disease Activity Index score.

Comment on: Pediatric systemic lupus erythematosus: Retrospective analysis of clinico-laboratory parameters and their association with systemic lupus erythematosus disease activity index score

Immunopathogenesis and spectrum of infections in systemic lupus erythematosus. Semin Arthritis Rheum 1996;25(5):318-36.

CLINICAL PROFILE AND RISK FACTORS OF MAJOR INFECTIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS

(6.) Wong CH, Chen TL, Lee CS, Lin CJ, Chen CP.nOutco-me of pregnancy in patients with systemic lupus erythematosus. Taiwan J Obstet Gynecol 2006;45(2):120-3.

SISTEMIK LUPUS ERITEMATOZUSLU 126 GEBENIN PERINATAL SONUCLARI/PERINATAL OUTCOMES OF 126 PREGNANCIES WITH SISTEMIC LUPUS ERYTHEMATOSUS

Echocardiography is a useful tool for documenting the valvular involvement and dysfunction as well as disease progression of the patients with systemic lupus erythematosus (SLE).1 It is usually asymptomatic; however, cases that needed valve replacement have been described.2