celecoxib

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cel·e·cox·ib

(sĕl′ə-kŏk′sĭb)

A nonsteroidal anti-inflammatory drug, C₁₇H₁₄F₃N₃O₂S, that selectively inhibits the formation of prostaglandins and is used primarily to treat pain and other symptoms of osteoarthritis, rheumatoid arthritis, and other joint and musculoskeletal conditions.

[Alteration of sele(ctive) + COX(-2 inh)ib(itor).]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

celecoxib

(ˌsɛləˈkɒksɪb)

an anti-inflammatory drug

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

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Noun

celecoxib - a Cox-2 inhibitor (trade name Celebrex) that relieves pain and inflammation without harming the digestive tract

Celebrex

Cox-2 inhibitor - an anti-inflammatory drug that fights pain and blocks Cox-2 activity without impeding the activity of Cox-1; increases the risk of heart attacks; "Cox-2 inhibitors reduce the symptoms of arthritis without endangering the stomach and kidneys"

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celecoxib

n celecoxib m

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References in periodicals archive ?

Celecoxib (Celebrex[R]), one of the most well-known cyclooxygenase-2 (COX-2) inhibitors, has been widely used for a wide range of morbidities since its launch in the late 1990s.

Prescribing patterns of celecoxib and prescribers' perceptions among three general hospitals in Northern Malaysia

The FDA mandated a cardiovascular safety trial of celecoxib (Celebrex[R]).

Warning: Common Pain Relievers Unsafe for Heart Patients: Fortunately, there are alternatives for those needing daily pain relief

Celecoxib, a nonsteroidal anti-inflammatory drug that acts via the selective inhibition of cyclooxygenase (COX)-2, has shown promising outcomes in several psychiatric diorders, including autistic disorder, schizophrenia, and depression.

Monoclonal Antibody a Promising Treatment for Depression

Consensi is a patent-protected combination of celecoxib, a non-steroidal anti-inflammatory drug, and amlodipine besylate, an antihypertensive calcium channel blocker.

Kitov Pharmaceuticals announces FDA approval of Consensi

Medicines with proprietary names ending in "coxib", such as celecoxib or etoricoxib, are traditionally thought of as the most selective in their effect on the COX-2 enzymes and were developed to reduce gastrointestinal (GI) toxicity associated with the use of traditional NSAIDs, but they have been characterized by some as having less favorable cardiovascular (CV) profiles than agents that are nonselective [5].

Are All Oral COX-2 Selective Inhibitors the Same? A Consideration of Celecoxib, Etoricoxib, and Diclofenac

Celecoxib (Figure 1(a)), a selective cyclooxygenase-2 (COX-2) inhibitor, has been widely used to treat arthritis for many years [1, 2].

Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS

Summary: A high performance liquid chromatographic method was developed and validated to simultaneously quantify citalopram with piroxicam, celecoxib and diclofenac sodium.

Liquid Chromatographic Method for Simultaneous Determination of Citalopram with NSAIDs in Bulk Drug, Pharmaceutical Formulation and Human Serum

PRECISION-ABPM, a four-month sub-study of the Cleveland Clinic-led PRECISION trial, evaluated the blood pressure effects of prescription ibuprofen (Advil[R], Motrin[R]), naproxen (Aleve[R]) and celecoxib (Celebrex[R]) among 444 patients, average age 62, with arthritis who had heart disease or were at increased risk for it.

Study Highlights Blood Pressure Risks of Popular Pain Drugs

Chondroitin Sulfate Similar to Celecoxib for Osteoarthritis of the Knee

Women's Health Update: Primary Care Issues: Fatigue and Osteoarthritis of the Knees

The researchers conducted animal studies tracking the effects of celecoxib on the growth of cancer cells from a tumour type known as neurofibromatosis type II (NF2).