granule

(redirected from Birbeck granules)
Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.

gran·ule

 (grăn′yo͞ol)
n.
1. A small grain or pellet; a particle.
2. Geology A rock or mineral fragment larger than a sand grain and smaller than a pebble, between 2 and 4 millimeters in diameter.
3. Astronomy One of the small, transient, luminous markings in the photosphere of the sun.
4. Biology A cellular or cytoplasmic particle, especially one that stains readily.

[Late Latin grānulum, diminutive of Latin grānum, grain; see gr̥ə-no- in Indo-European roots.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

granule

(ˈɡrænjuːl)
n
1. a small grain
2. (Geological Science) geology a single rock fragment in gravel, smaller than a pebble but larger than a sand grain
3. (Astronomy) astronomy another name for granulation5
[C17: from Late Latin grānulum a small grain]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

gran•ule

(ˈgræn yul)

n.
1. a little grain.
2. a small particle; pellet.
[1645–55; < Late Latin grānulum small grain. See grain, -ule]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.granule - a tiny graingranule - a tiny grain        
microsome - a tiny granule in the cytoplasm that is where protein synthesis takes place under the direction of mRNA
chondrule - small granule (of e.g. chrysolite) found in some meteoric rocks
grain - a relatively small granular particle of a substance; "a grain of sand"; "a grain of sugar"
plastid - any of various small particles in the cytoplasm of the cells of plants and some animals containing pigments or starch or oil or protein
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.

granule

noun grain, scrap, molecule, particle, fragment, atom, crumb, jot, speck, iota granules of coarse-grain sea salt
Collins Thesaurus of the English Language – Complete and Unabridged 2nd Edition. 2002 © HarperCollins Publishers 1995, 2002
Translations
حُبيْبَه
zrnko
lille korn
smákorn, ögn
granuliuotasgrūdėtas
granulagraudiņš

granule

[ˈgrænjuːl] N [of sugar etc] → gránulo m
Collins Spanish Dictionary - Complete and Unabridged 8th Edition 2005 © William Collins Sons & Co. Ltd. 1971, 1988 © HarperCollins Publishers 1992, 1993, 1996, 1997, 2000, 2003, 2005

granule

[ˈgrænjl] ngranule m
Collins English/French Electronic Resource. © HarperCollins Publishers 2005

granule

nKörnchen nt
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

granule

[ˈgrænjuːl] ngranello
Collins Italian Dictionary 1st Edition © HarperCollins Publishers 1995

granule

(ˈgrӕnjuːl) noun
a very small particle. a granule of sugar.
ˈgranular adjective
ˈgranulated (-lei-) adjective
broken into tiny particles. granulated sugar.
Kernerman English Multilingual Dictionary © 2006-2013 K Dictionaries Ltd.

gran·ule

n. gránulo, partícula pequeña formada de gránulos;
acidophil ______ acidófilo, que acepta colorantes ácidos;
basophil ______ basófilo, que acepta colorantes básicos.
English-Spanish Medical Dictionary © Farlex 2012

granule

n gránulo
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
References in periodicals archive ?
Electron microscopy of the tumor cells demonstrated the presence of Birbeck granules (Figure 2e) in the majority of histiocytes examined.
In early lesions, scalloped macrophages dominate the histology, but most well-developed lesions have a mixture of the above.14 Immunohistochemical studies show negative staining for S-100, CD1a, and Birbeck granules, and positive staining for the surface markers CD68 and factor XIIIa.15 Our patient had typical lesion involving typical sites and histopathology of skin lesions showed foamy histiocytes and occasional multinucleated giant cell in dermis.
The typical non-Langerhans' foamy histiocytes that lacked Birbeck granules, located in a polymorphic granuloma with xanthogranulomatosis was shown.
These cells express S100 protein, CD1a, and langerin (CD207) and contain intracytoplasmic Birbeck granules. They are named after Paul Langerhans (1847-1888), a German pathologist, physiologist, and biologist who discovered these cells in the skin and postulated that they were possibly nerve endings.
(1,2) The major diagnostic features of LCH are expression of CD1a and S100 as well as ultrastructural Birbeck granules. (3) Its presentation can differ from a mild bone lesion to a multi-systemic evolved malignant neoplasm; however, the latter outcome is almost rare.
Langerhans cells are dendritic antigen presenting cells with distinctive convoluted nuclear contour, presence of Birbeck granules on electron microscopy and positive staining with S-100 and CD1a.