Release date- 29072019 - Cell freezing (cryopreservation) - which is essential in cell transfusions as well as basic biomedical research - can be dramatically improved using a new polymeric
cryoprotectant, discovered at the University of Warwick, which reduces the amount of 'anti-freeze' needed to protect cells.
However, the origin of such abnormalities is usually determined by the temperature reduction or to the exposure to toxicity of
cryoprotectant solution.
Patent FR 1553716: This patent, co-owned by MaaT Pharma and INRA, covers the composition and the application of the
cryoprotectant used in MaaT Pharma's proprietary production process that helps to preserve the full diversity of the gut microbiome.
MATSUMOTO, Japan, April 24, 2019 -- A team of Japanese researchers has demonstrated preserving frozen animal cells without a
cryoprotectant agent (CPA), a substance that can protect biological material from freezing damage.
(2017) compared the viability of free and microencapsulated Pediococcus acidilactici ATCC 8042 in calcium alginate and co-coating with calcium alginate and chitosan by extrusion technique with subsequent freeze-drying using 10% (w/w) of skimmed milk as
cryoprotectant, compared to simulated gastric juice and bile tolerance assays and reported that probiotic cell mortality significantly reduced when microencapsulated probiotics were compared to free cells.
The product utilises a proprietary non-DMSO
cryoprotectant, affording optimal cell protection and streamlined preparation in the OR.
Testicular tissue and ejaculated spermatozoa were frozen after addition of a commercially available
cryoprotectant according to the instructions of the supplier.
Vitrification is a physical process involving rapid freezing with a low volume of a concentrated solution
cryoprotectant (antifreeze) without forming ice crystals (Campos-Chillon et al., 2009).
Li, "Inhibition of frozen storage-induced oxidation and structural changes in myofibril of common carp (Cyprinus carpio) surimi by
cryoprotectant and hydrolysed whey protein addition," International Journal of Food Science & Technology, vol.
were suspended in 10% dimethyl sulfoxide (DMSO) as a
cryoprotectant, and
Explants survival percentage (a) and percentage of shoot formation (b) from lateral buds encapsulated in sodium alginate matrix after 30 days in culture, after incubation in PVS2
cryoprotectant solution for different times (0, 15, 30, 60 and 120 minutes), before immersion in LN.