L-dopa


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Related to L-dopa: levodopa, dopamine, Mucuna pruriens

L-do·pa

 (ĕl-dō′pə)
n.
An isomer of dopa that is converted in the brain to dopamine and is used in synthetic form to treat Parkinson's disease. Also called levodopa.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

L-dopa

(ɛlˈdəʊpə)
n
(Biochemistry) a substance occurring naturally in the body and used to treat Parkinson's disease. Formula: C9H11NO4. Also called: levodopa
[C20: from L-d(ihydr)o(xy)p(henyl)a(lanine)]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

L-do•pa

(ˌɛlˈdoʊ pə)

n.
the levorotatory isomer of dopa, converted in the brain to dopamine: used in synthetic form chiefly for treating parkinsonism. Also called levodopa.
[1935–40]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.L-dopa - the levorotatory form of dopa (trade names Bendopa and Brocadopa and Larodopa); as a drug it is used to treat Parkinson's disease
Bendopa, Brocadopa, Larodopa, levodopa
dihydroxyphenylalanine, dopa - amino acid that is formed in the liver and converted into dopamine in the brain
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
Focusing on levodopa (L-dopa), the primary treatment for Parkinson's disease, they identified which bacteria out of the trillions of species is responsible for degrading the drug and how to stop this microbial interference.
Gut Microbes Eat Our Medication
Adhesion in these systems is mediated by the amino acid L-3,4-dihydroxyphenylalanine (L-DOPA).
Catecholic Compounds in Ctenophore Colloblast and Nerve Net Proteins Suggest a Structural Role for DOPA-Like Molecules in an Early-Diverging Animal Lineage
SLS-006 has shown efficacy in early-stage Parkinson's disease patients as a monotherapy and as a potential adjunctive therapy in late-stage Parkinson's disease patients upon co-administration with a low dosage of L-Dopa.
Ligand Partner Seelos Therapeutics Becomes a Public Company Following Reverse Merger
Objective: To assess effects of levodopa (L-dopa) on personality disturbances and dysexecutive symptoms in patients with idiopathic Parkinson's disease (PD).
SHORT COMMUNICATION - EFFECT OF LEVODOPA ON PERSONALITY DISTURBANCES AND DYSEXECUTIVE SYMPTOMS IN PATIENTS WITH IDIOPATHIC PARKINSON'S DISEASE
Objectives: To determine (i) levodopa (L-Dopa) responsiveness on cortical functions, health related quality of life and fatigue severity (ii) relationship between cortical functions, health related quality of life and fatigue severity post L-Dopa treatment of patients with idiopathic Parkinson's Disease (I-PD).
Short Communication - L-Dopa response to Cortical Dysfunctions, health related quality of life and Fatigue Severity in Idiopathic Parkinson's disease
Due to this loss, exogeneous L-dopa cannot be metabolized properly leading to non-physiological dopamine release and LID eventually.
Striatal Neurotransmitter Release-related Presynaptic Proteins in L-dopa Induced Dyskinesia in a Model of Parkinsonism
It was designed to deliver a precise dose of a dry powder formulation of L-dopa to the lung.
FDA Accepts Acorda NDA for Inbrija (levodopa inhalation powder)
A similar study but with a different objective was conducted by Ferrarin et al.; they used a marker-based system to examine the effects of subthalamic stimulation on gait kinematics and kinetics in PD, and they were able to find clinical differences in the effects produced by medication (L-dopa) and DBS [12].
Accuracy of Markerless 3D Motion Capture Evaluation to Differentiate between On/Off Status in Parkinson's Disease after Deep Brain Stimulation
Baker (Phillipsburg, NJ, USA), ferulic acid was from ChromaDEX (Irvine, California), gallic acid was from Alfa Aesar (Ward Hill, MA, USA), kojic acid and (s)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid (L-dopa) were from Acros (New Jersey, USA), and methyl paraben was from Supelco (Bellefonte, USA).
Kinetics Investigation on Mushroom Tyrosinase Inhibition of Proso Millet
As most patients in these studies were treated with a combination of L-DOPA and carbidopa, it is possible that one or both of these drugs could exhibit anti-cancer properties and contribute to the lower incidence of cancer observed in these patients.
This Parkinson's disease drug shows anticancer effects: Study
Sudden discontinuation of L-Dopa, which has a short half-life, can cause muscle rigidity, difficulty in spontaneous respiration, and requirement of mechanical ventilation (1).
An Experience of General Anesthesia in a Case of Parkinson's Disease/Parkinson Hastaligi Olan Olguda Genel Anestezi Deneyimi
Background: Parkinson's disease (PD) patients with long-term levodopa (L-DOPA) treatment are suffering from severe circadian dysfunction.
Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease

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