In step two, they add a dementia-specific biomarker, give a result, is likely called
tau protein, and run further tests on those people who tested positive in step one.
By targeting specific pathological forms of
Tau protein, immunization with anti-Tau vaccines has become an important strategy for the treatment of AD and other Tauopathies because it has the potential to prevent and reduce the development and spread of Tau pathology throughout the brain.
Neurofibrillary tangles composed of aggregated
tau protein are one of the pathological features of Alzheimer's disease (AD).
Neurofibrillary tangles composed of aggregated
tau protein is one of the pathological features of Alzheimer's disease (AD).
Women appeared to have better connectivity between the regions where
tau protein builds up - and this had implications for the brain, the study said.
Wherever tangles of the
tau protein appear, brain tissue dies, triggering the confusion and memory loss that are hallmarks of Alzheimer's.
Lack of such a cleansing operation due to lack of sleep, allows the accumulation of A-beta plagues around brain neurons which lead to an abnormal concentration of toxic
tau protein (known as tangles) inside neurons.
has inked a research collaboration with the LuMind IDSC Foundation (LuMind IDSC) involving use of Cerveau's investigational imaging agent (MK-6240) in a multicenter clinical trial aimed at assessing accumulation of misfolded
tau protein in people with Down syndrome, the company said.
Page 17 Dr Rosa Sancho, head of research from Alzheimer's Research UK said: "Lonafarnib should be explored as a potential way to target the
tau protein. But this early work in mice still has a long way to go before we'll know whether it could be a medicine that benefits people with dementia."
A research team of Seoul National University has developed a blood test-based Alzheimer's disease diagnosis technology by checking for abnormal deposition of
tau protein in the brain, the science ministry said Monday.
PSP is a rare neurological condition that causes severe problems with walking, balance, speech, swallowing and vision as a result of the accumulation of aggregates of the
tau protein in the brain.
Results: There are many amounts of data supporting the view that AD pathogenesis so far there mainly are A[sz] toxicity,
tau protein, gene mutation, synaptic damages, intermediate neurons and network abnormalities, changes in mitochondrial function, chemokines, etc., Its nosogenesis may be involved in multiple theories and involved in multiple molecular signaling pathways, including A[sz],
tau protein, and synaptic anomaly; mutual relationship between the mechanisms urge jointly neuronal degeneration.