mefenamic acid


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mef·e·nam·ic acid

 (mĕf′ə-năm′ĭk)
n.
A crystalline compound, C15H15NO2, used as an anti-inflammatory drug and as an analgesic.
[(di)me(thyl) + alteration of phen(yl) + am(inobenzo)ic acid.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.mefenamic acid - a nonsteroidal anti-inflammatory and analgesic drug (trade name Ponstel) used to treat mild pain (especially menstrual cramps)
Ponstel
nonsteroidal anti-inflammatory, nonsteroidal anti-inflammatory drug, NSAID - an anti-inflammatory drug that does not contain steroids; "NSAIDs inhibit the activity of both Cox-1 and Cox-2 enzymes"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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The most commonly prescribed NSAIDs were flurbiprofen, they were prescribed by 40% respondents, paracetamol 16%, nimesulide 14%, ibuprofen 10%, diclofenac, naproxen 8% and mefenamic acid 4%.
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Among the drugs of this family, mefenamic acid is more effective than others because it reduces the production of PGs by COX enzymes and decreases the activity of PGs in the uterus through inhibition of its receptors.
The efficacy of zinc administration in the treatment of primary dysmenorrhea
To treat essential menorrhagia, mefenamic acid and tranexamic acid are being used.
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One study compared 500mg of oral mefenamic acid and placebo and found that mefenamic acid was ineffective during the procedure yielding decreased VAS scores after the procedure.1 Cervical and uterine manipulation leads to prostaglandin release which might induce postprocedural pain.
Comparison of placebo and intrauterine lidocaine with/or without rectal diclofenac sodium suppositories used in office endometrial biopsy
Comparison of the effects of Matricaria chamomila (Chamomile) extract and mefenamic acid on the intensity of premenstrual syndrome.
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