major histocompatibility complex

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Related to major histocompatibility complex: human leukocyte antigen

major histocompatibility complex

n. Abbr. MHC

A group of genes in humans and most other vertebrates that code for cell-surface glycoproteins (called MHC molecules) which function in the immune system and also are principally responsible for determining tissue compatibility in transplants.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

major histocompatibility complex

(Genetics) the full name for MHC

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

MHC

major histocompatibility complex: a group of genes that determine histocompatibility antigens, located in humans on the sixth chromosome. Compare HLA.

Translations

complexe majeur d’histocompatibilité

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References in periodicals archive ?

The antigens of the HLA system are determined by genes present in the major histocompatibility complex which is located on the short arm at the 6th chromosome (6p21.3) in humans and extends over some 4 centimorgans of DNA, about 4 x[10.sup.6] base pair.

THE HUMAN LEUKOCYTE ANTIGEN SYSTEM AND TRANSPLANTATION IMMUNOLOGY/SISTEM HUMANIH ANTIGEN LEUKOCITA ITRANSPLANTACIONA IMUNOLOGIJA

Kretsovali, "Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes," Molecular and Cellular Biology, vol.

Pulling a Ligase out of a "HAT": pCAF Mediates Ubiquitination of the Class II Transactivator

Abbreviations Ab: Antibody ABOi: ABO-incompatible AECA: Autogenous anti-endothelial cell antibody AMR: Antibody-mediated rejection APC: Antigen presenting cell A[T.sub.1]R: Angiotensin type 1 receptor AVA: Anti-vimentin antibodies CMR: Cell-mediated rejection DSA: Donor-specific antibody EDIL3: EGF-like repeats and discoidin I-like domain 3 EMT: Endothelial-to-mesenchymal transition E[T.sub.A]R: Endothelin-1 type A receptor HLA: Human leukocyte antigen FLT3: Fms-like tyrosine kinase 3 ICAM4: Intercellular adhesion molecule 4 LG: Laminin-like globular domain MICA: Major histocompatibility complex class I related chain A antigen Treg: Regulatory T-cell.

Endothelial Cells in Antibody-Mediated Rejection of Kidney Transplantation: Pathogenesis Mechanisms and Therapeutic Implications

Influence of combinations of human major histocompatibility complex genes on the course of HIV-1 infection.

Very recent HIV infection accompanied by Pneumocystis jirovecii pneumonia and Mycobacterium avium complex immune reconstitution inflammatory syndrome: a case report

In humans, major histocompatibility complex controlled by the genes located on chromosome 6 is responsible for ensuring compatibility between donors and recipients.

Report Published: "Global Transplant Diagnostics Market 2016-2020"

Cathepsin S is involved in the assembly of the major histocompatibility complex II protein, and by interfering with this process, the effector T-helper cell response may be muted and T-cell interaction with B cells may be decreased.

TRACTISS ends rituximab hopes for Sjogren's syndrome

(2) One of these risk genes, on chromosome 6, is in the major histocompatibility complex and has the strongest association with schizophrenia (P = [10.sup.-31]).

'Druggable' genes, promiscuous drugs, repurposed medications: thanks to disruptive genetic breakthroughs in psychiatry, there are glittering lights at the end of the psychopharmacotherapeutic discovery tunnel

Comparative organization and function of the major histocompatibility complex of domesticated cattle.

Short Communication - SEQUENCE DIVERSITY OF BoLA-DRB3 GENE IN PAKISTANI DROMEDARY CAMEL

Called the major histocompatibility complex, or MHC, this DNA chunk carries information used by the immune system to help identify invaders.

Schizophrenia tied to synapse pruning: variants of immune system gene implicated in mental disorder

Specialized cells in the thymus interact with a molecule known as the Major Histocompatibility Complex class II (MHCII) to "teach" T cells to differentiate between normal tissues and organs, and foreign invaders.

New pathway to possible IBD cure: scientists are zeroing in on causes of gut diseases, leading to possible new treatments

PLX cells, and other MSC, affected complex pathways in order to prevent the priming of Type 1 T helper cell (Th1) responses towards major histocompatibility complex mismatches.