actinomycin


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ac·tin·o·my·cin

 (ăk-tĭn′ō-mī′sĭn, ăk′tə-nō-)
n.
Any of a class of peptide-containing, often toxic antibiotics that are obtained from soil bacteria.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

actinomycin

(ˌæktɪnəʊˈmaɪsɪn)
n
(Pharmacology) any of several toxic antibiotics obtained from bacteria of the genus Streptomyces, used in treating some cancers; the most commonly used is dactinomycin (actinomycin D)
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

ac•tin•o•my•cin

(ækˌtɪn oʊˈmaɪ sɪn, ˌæk tə noʊ-)

n.
any of a group of related antibiotics derived from streptomyces bacteria, used in the treatment of various cancers.
[1935–1940; actinomyc (es) + -in1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.actinomycin - any of various red antibiotics isolated from soil bacteria
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
Dactinomycin is an actinomycin indicated for the treatment of: adult and pediatric patients with Wilms tumor, as part of a multi-phase, combination chemotherapy regimen.
X-GEN Pharmaceuticals, Inc - The Release of Dactinomycin for Injection, USP
(4) Examples of antibiotics from Actinobacteria include streptomycin, streptothricin, and actinomycin. (4,6) In addition to their antimicrobial activity, previous research indicated that Actinobacteria are a good source of promising compounds with herbicidal, antitumor, antifungal and anthelminthic activities.
Detection of antibiotic-producing Actinobacteria in the sediment and water of Ma'in thermal springs (Jordan)
All patients followed UKCCLG (United Kingdom Children Cancer and Leukemia Group) protocol for therapy.Two-drug preoperative chemotherapy with Vincristine and Actinomycin was used in non-metastatic tumour for 4 cycles and Doxorubicin added for metastatic tumours and total duration of preoperative chemotherapy was increased to 6 cycles.
Short term surgical outcomes of Wilms tumour from a single institute
After Pre-Chemotherapy Workup, Multidrug Chemotherapy (Etoposide, Methotrexate, Actinomycin - D, Cyclo-phosphamide, Oncovin / Vincristine) was started and the patient was regularly monitored by CBCs, LFTs, RFTs and Serum [beta] HCG.
UNUSUAL PRESENTATION OF GESTATIONAL TROPHOBLASTIC DISEASE
[10] Chemotherapeutic agents used in the treatment of STS are bleomycin, 5-fluorouracil, methotrexate, vincristine, actinomycin, doxorubicin, cyclophosphamide, or dacarbazine.
Stewart--Treves Syndrome: A Case Report and Review of Literature
1984, V RP.SA retrospective [21] Cytoxan A Actinomycin Burdach et al.
Role of High-Dose Chemotherapy and Autologous Hematopoietic Cell Transplantation for Children and Young Adults with Relapsed Ewing's Sarcoma: A Systematic Review
We describe a case of a patient who continued to progress during treatments with carboplatin, paclitaxel, melphalan, actinomycin D, and radiotherapy but achieved 18 months of progression free survival (PFS) and an improved quality of life with oral capecitabine despite her diffusely metastatic disease.
Oral Capecitabine Achieves Response in Metastatic Eccrine Carcinoma
After the definitive histological diagnosis and multidisciplinary evaluation, the oncologist proposed an adjuvant therapy of six cycles with vincristine, actinomycin D, and cyclophosphamide, which was accepted by the patient.
Unexpected Liver Embryonal Sarcoma in the Adult: Diagnosis and Treatment
In some of the experiments, the HUVECs were stimulated by a transcription inhibitor, actinomycin D (5 [micro]g/ml), before [H.sub.2][O.sb.2] treatment and harvested after a certain time.
miR-125a Suppresses TrxR1 Expression and Is Involved in [H.sub.2][O.sb.2]-Induced Oxidative Stress in Endothelial Cells
One such colored compound is actinomycin which are bicyclic chromopeptide lactone antineoplastic antibiotics produced by various Streptomycetes.
A Preliminary Assessment of Yellow Pigment from Streptomyces parvulus C5-5Y
Subsequently, by using bovine thyroid cells, Knopp and co-workers confirmed this observation (1970) as well as an inhibitory effect of actinomycin D when added together with TSH.
The Thyroid [Na.sup.+]/[I.sup.-] Symporter: Molecular Characterization and Genomic Regulation/Tiroid [Na.sup.+]/[I.sup.-] Simporter: Molekuler Tanimlamasi ve Genomik Kontrolu

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