The Rauwolfia alkaloids extracted from the roots, leaves and seeds, medically it is important therapeutic agent both as antihypertensives and as sedatives.
All decongestants can interact adversely with monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, indomethacin, beta blockers, methyldopa, some general anesthetics, digitalis, antihypertensives, rauwolfia alkaloids, other central nervous system (CNS) stimulants, and possibly theophylline.